Kitajski znanstveniki naj bi odkrili sveti gral: Uspelo naj bi jim zaustaviti proces staranja

Gre za resnično fenomenalno odkritje, če se bo seveda izkazalo kot delujoče, splošno in brez stranskih učinkov. Kitajski znanstveniki iz prestižne Kitajske akademije znanosti in umetnosti so v znanstveni reviji Cell objavili članek, da so v primatih v desetih sistemih organov, med njimi tudi v možganih, uspeli zaustaviti proces staranja. To predstavlja prelomnico v razumevanju staranja. Študija poroča, da eksperiment ni le upočasnil staranja, temveč ga v celoti obrnil pri podganah. To naj bi dosegel z epigenetskim reprogramiranjem – ponastavitvijo epigenetske ure, ki deluje kot celični “koledar” staranja. Metoda, ki jo je razvil biolog David Sinclar, temelji na indukciji Yamanaka faktorjev, vendar z izboljšavo: uporablja daljši in ciklični postopek, ki preprečuje nastanek teratoma (vrste tumorja), glavnega tveganja pri tej tehniki.

Highlights

  • Genetically enhanced senescence-resistant cells exhibit anti-aging effects
  • These SRCs counteract systemic aging in primates
  • SRCs boost cognitive and reproductive rejuvenation
  • SRCs deliver geroprotection through exosomal cargoes

Summary

Aging is characterized by a deterioration of stem cell function, but the feasibility of replenishing these cells to counteract aging remains poorly defined. Our study addresses this gap by developing senescence (seno)-resistant human mesenchymal progenitor cells (SRCs), genetically fortified to enhance cellular resilience. In a 44-week trial, we intravenously delivered SRCs to aged macaques, noting a systemic reduction in aging indicators, such as cellular senescence, chronic inflammation, and tissue degeneration, without any detected adverse effects. Notably, SRC treatment enhanced brain architecture and cognitive function and alleviated the reproductive system decline. The restorative effects of SRCs are partly attributed to their exosomes, which combat cellular senescence. This study provides initial evidence that genetically modified human mesenchymal progenitors can slow primate aging, highlighting the therapeutic potential of regenerative approaches in combating age-related health decline.

Ključno vprašanje je seveda, kaj to odkritje pomeni za prihodnost človeštva. Namreč, to nas postavlja pred možnost, da bi v prihodnosti lahko staranje obravnavali kot zdravljivo bolezen. Če se bo to odkritje potrdilo in varno preneslo na ljudi, bi lahko imelo večplastne posledice. Na hitro nekaj premislekov o možnih posledicah. 

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Lažni alarmi zaradi “ruskih” dronov so postali modus operandi evropske provojne propagande

Doslej so se vsi, ampak prav vsi alarmi, zaradi vdora “ruskih” raket in dronov in škode na civilnih objektih v državah EU ter zaradi “ruskega” trganja podvodnih komunikacijskih kablov v Baltiku izkazali kot lažni.

Čemu služi ta propaganda? Da nam bodo lažje prodali, da naj pozabimo na razvoj in blaginjo in proračunska sredstva raje namenimo za nakupe (ameriškega in izraelskega) orožja? Da nam bodo lažje prodali salto mortale, da je bolje proizvajati dizelske tanke kot električne avte? Da nam bodo lažje prodali cenzuro tudi v družbenih omrežjih?

Ja, ruska agresija na Ukrajino je neupravičljiva iz vidika mednarodnega prava (čeprav to za velike države pač ne velja oziroma si vzamej pravico, da ne spoštujejo pravil, ki so jih postavile za druge. In seveda ne velja za Izrael, ki je iznad vsega). Toda ruska agresija je omejena na Ukrajino, nikoli ni bilo enega samega znaka (vsaj v besedi), da bi jo Rusi želeli razširiti. Zato je res žaljivo za naš intelekt to ustvarjanje prazne rusofobne panike.

“The man who launched a UAV at Frankfurt airport turned out to be an amateur operator. The police detained a 41-year-old Croatian”

To create panic at the European Union level and accuse Russia, the authorities of EU countries have decided to “Shut down” major airports due to amateur drone operators.

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Kako je CIA prek nevladnih organizacij pripravila teren v Ukrajini

Prva slika: Mike Benz, nekdanji visoki uslužbenec State Departmenta, razlaga, kako obveščevalne agencije uporabljajo vladno financirane “nevladne organizacije” (NVO) za ugrabitev civilne družbe drugih držav in kako so ZDA in njihovi partnerji prevzeli nadzor nad Ukrajino. Zdaj je zdaj ključna tarča Gruzija.

Druga slika: USAID prek Internews od 2001 naprej sistematično ustvarja novo medijsko krajino v Ukrajini.

Emmanuel Todd: Europeans, crazy people who think they can act as winners and impose conditions despite being the biggest losers of the war

Fascinating geopolitical analysis by Emmanuel Todd, one of the very few great French intellectuals we have left. I added English subtitles for you.

He believes – as I do – that, fundamentally the US is accepting what he calls “defeat” against not only Russia but China as well, and that Trump is effectively trying – clumsily – to manage this defeat and to adapt the US to multipolarity.

He says that the US’s defeat in Ukraine isn’t like Afghanistan or Iraq but that it represents what he calls “America’s first major strategic defeat of its history.”

In the war, he says Russia has become “the shield of all the rest of the world who can’t stand US guardianship of global finance [and] the exploitation of the working populations in the rest of the world by Westerners.”

As he puts it, Russia has demonstrated “that they were able to face the whole West,” and with the rise of BRICS financial systems, this represents nothing less than “the end of the American imperium” – a defeat Trump must now manage.

With regards to China he says that the US have in fact “given up” trying to contain them because the balance of power now makes it impossible. He points to “Chinese naval production that will soon make the US Navy a dwarf navy”, “US aircraft carriers [that] are irrelevant facing hypersonic missiles” and the fact that China managed to “put the Americans under embargo” for rare earth exports.

Arguments that undoubtedly will sound very familiar to my readers because I make the same ones in my articles (like this one: https://arnaudbertrand.substack.com/p/has-america-in-fact-already-withdrawn?r=4r0pw), which I know Todd reads because, full disclosure, we know each others.

In this picture, Todd characterizes (quite rightly) Europeans as “crazy, we are dealing with crazy people” who think they can act as winners and impose conditions despite being the biggest losers of the war.

He is particularly virulent against the media and the general intellectual climate in Europe, speaking of a “process of intellectual and moral degeneration” where “all notions of truth, of honor, of reflection” are being lost.

He says that the end of the US’s global hegemony doesn’t mean they won’t relinquish control of what they still do control, specifically Europeans.

Vir: Arnaud Bertrand

Ameriška sovražna klima spodbuja znanstvenike k vračanju nazaj v Evropo

Število prijav evropskih znanstvenikov, ki delujejo na ameriških univerzah, na evropske raziskovalne projekte se je povečalo za 5-krat. Glavni razlog naj bi bili zmanjšanje sredstev za znanost pod Trumpom, naraščajoče sovražna klima v Ameriki in večja akademska svoboda govora v Evropi.

Če karikiram in malce pretiravam: gre za obraten proces, kot se je zgodil v 1930-ih letih v Evropi, ko je ogromno znanstvenikov židovskega porekla emigriralo v ZDA in pomagalo k vzpostaviti ZDA kot raziskovalnega središča. Danes imamo opravka z eksodusom najboljših kitajskih znanstvenikov (kitajski program Thousand talents) in evropskih znanstvenikov (program ERC) iz ZDA nazaj domov. Trump je najboljša stvar, ki se je lahko zgodila kitajski in evropski znanosti ter posledičnemu tehnološkemu napredku v teh državah.

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A recent call for a multimillion-euro program run by the EU’s top research council saw a fivefold increase in U.S.-based applicants seeking to relocate to European institutions to pursue their research ambitions, according to new data seen by POLITICO.

The fresh wave of interest from U.S.-based researchers for European research grant money comes amid an increasingly hostile climate for academic research under the Trump administration.

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Was Scandinavia’s Russian Drone Scare A False Flag To Crack Down On Russia’s Shadow Fleet?

Andrew Korybko

It’s highly suspicious that Zelensky just claimed without any evidence that they were launched by Russian tankers and subsequently demanded that Europe close the straits to its shipping in response.

Unknown drones recently flew in close proximity to Danish and Norwegian airports, prompting speculation among some that they were Russia’s delayed hybrid retaliation against NATO for backing Ukraine’s drone flights in proximity to Russia’s own airports over the past few years. No evidence has emerged in support of that hypothesis, but Zelensky still dishonestly passed off such claims as fact during his speech at the latest Warsaw Security Forum.

According to him, “there is growing evidence that Russia may have used tankers in the Baltic Sea to launch drones – the drones that caused major disruption in Northern Europe. If tankers used by Russia are serving as drone platforms, then such tankers should not be free to operate in the Baltic. This is de facto Russia’s military activity against European countries, so Europe has the right to close straits and sea routes to protect itself.”

His proposal for NATO to close the Danish Staits to Russian shipping on this pretext, which would amount to an illegal blockade that could thus legitimize offensive action by Russia in self-defense, was predictable given Ukraine’s and some of its patrons’ interest in escalating the bloc’s tensions with Russia. In fact, it might even be the case that this was the false flag that Russia’s Foreign Intelligence Service twice warned could soon be staged by the UK and Ukraine, albeit ultimately taking a different form.

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Kuha se nov izraelsko-ameriški napad na Iran